CellSeal® CryoCase™
Rigid container designed specifically for cell and gene therapies
![BS - CellSeal CryoCase - Technical Data Sheet[74]](https://www.biolifesolutions.com/wp-content/uploads/2024/09/BS-CellSeal-CryoCase-Technical-Data-Sheet74.jpg)
CellSeal® CryoCase™:
The Next Generation of CGT Container
The CryoCase is the first ever cryo-compatible rigid container designed for closed-system fill and retrieval for larger volumes of fluid (<75mL). The container is transparent, enabling improved end user compliance with USP 790, USP 1790, and other international visible inspection methods, and manufactured under strict environmental and processing controls designed to limit common sources of particulates in single-use disposable manufacturing.
Early testing has shown viability equivalency with existing bags for multiple cell types.
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Request your
sample here
Get in touch
BioLife Solutions Inc.
3303 Monte Villa Parkway,
Suite 310, Bothell , WA 98021 USA
For assistance, please call us Monday
through Friday (9:00 am to 5:00 pm PST) at:
Toll Free (North America): +1.866.424.6543
Direct: +1.425.402.1400
Fax: +1.425.402.1433
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Rethink the standard,
replace the bag.
The CellSeal CryoCase has been designed specifically for the cell and gene therapy industry and outpaces cryogenic bag standards on many levels. Early feedback on the CryoCase has been strong.
- Versatile fill volumes: 25 mL, 50 mL and 75 mL
- XL fill line for easier sterile welding
- Built-in spike ports for closed-system retrieval
- Transparent, glass-like structure for improved inspectability
- Rigid design with inherent dampening mechanisms to protect samples during handling
- Convenient hanger mechanism to engage with fill machines, bag poles or other laboratory equipment
- Exterior Dimensions (sealed, H x W x D): 136 mm x 136 mm x 14 mm
- Weight (sealed without fill lines): 74 g
- Material: COC; Spike ports: EVA
- Designed to minimize particulate contamination and enhance the safety and performance of cryopreserved cell therapies.
- Tested to demonstrate superior durability, leak-proof construction, and fracture resistance when compared to cryobags.
- Evaluated for equivalent performance in terms of cell viability and recovery, ensuring consistent results without compromising on safety.
- Developed to simplify the cryopreservation process and eliminate the need for multiple operators and additional steps like air evacuation, making it a more efficient and user-friendly alternative to cryobags.
- Evidence of comparable freezing and thawing rates between the CryoCase and traditional cryobags.
- Clear for improved inspectability, ensuring better particulate detection, essential for ensuring the quality of cell and gene therapies.
![BS - CryoCase Webpage - Documents Section IMAGE[19]](https://www.biolifesolutions.com/wp-content/uploads/2024/11/BS-CryoCase-Webpage-Documents-Section-IMAGE19-scaled.jpg)
Additional CryoCase resources may be downloaded here:
Looking for a compatible,
closed-system for
fluid management?
Use the Signata CT-5™ platform for final fill, media formulation, and bioreactor fill and wash.
As a fluid transfer system, the Signata CT-5 allows reversible flow direction from up to 11 input/output points and three-way control valves allowing closed movement between multiple points.
The CellSeal CryoCase was designed to be compatible with this system.
The CellSeal® CryoCase™ Stand and Carrier Accessories are designed to enhance the usability of the CryoCase system, making it easier to handle during storage and transportation. These accessories accommodate up to 10 CryoCase units.
CryoCase Carrier
Specifically designed for the safe transport of CryoCase units installed in the stand, the carrier allows easy handling with cryogenic gloves. It provides a secure attachment to prevent dislodging during transport, ensuring the safety of the units.
CryoCase Stand
This accessory ensures a secure vertical orientation of the CryoCase units during filling and storage. It is validated for use at extreme cryogenic temperatures (down to -196°C), making it suitable for freezing applications, including liquid nitrogen immersion.
Both accessories are non-sterile and can be steam sterilized at 121°C.
They should be stored in a clean, dry place at room temperature until needed