CellSeal® Cryogenic Vials

Closed-system cryogenic vials for CGT manufacturing

CellSeal Cryogenic Vials

CellSeal and CellSeal Clear Access Cryogenic Vials

cellseal clear access product

CellSeal® Cryogenic Vials are the first purpose-built rigid containers used in the cell and gene therapy industry. Unlike traditional screw cap vials and stoppered vials, the hermetically sealed access ports withstand the challenges of -196°C storage without compromising CCI.

With a full suite of accessories and filling systems, vials can be filled manually or with high throughput systems- ideal for both autologous and allogeneic products.

  • 5mL and 2mL vial sizes
  • Swabbable or capped Luer-compatible fill ports
  • USP Class VI compliant materials
  • Certificate of Compliance per lot provided with each purchase
  • Cryogenic vials can be safely handled when frozen
  • Designed for extreme temperature conditions
  • Closed-system design prevents sample leakage
  • Microbial barrier vent for filling and withdrawal at atmospheric pressure
  • Conically-shaped retrieval port for maximum sample recovery
  • Loading ports configured for syringes, pipettes, or needleless Luer fittings
  • Compatible with the Sexton AF-500 Automated Fill and Seal System and the Signata CT-5 Fluid Management System

Frequently
Asked Questions

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CellSeal Vials are validated in actual conditions. CellSeal Vials were subjected to freezing, storage in liquid nitrogen, a drop test, frozen transportation, and thawing. Following thawing, a series of container integrity tests were performed, including dye and bacterial immersion studies. All vials met the defined criteria for each test.

All specimen contacting materials are manufactured from USP Class VI compliant materials, and have been subjected to biological safety testing that included genotoxicity, cytotoxicity, sensitization, irritation, hemocompatibility, and acute systemic toxicity.

Yes. A Certificate of Compliance per lot number is provided to the customer with each purchase.

CellSeal Vials have demonstrated low levels of extractables during a leachables study.

The CellSeal Vial has an expiration date of three years from date of manufacture.

Please refer to the corresponding recommended instructions for guidance (IFU) on how to use the CellSeal Vial.

The expansion profile of different solutions are dependent on content, concentration and freezing process. We suggest evaluating the expansion profile of your product in CellSeal Vials under the intended conditions of use. Please contact us for additional information.

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ThawSTAR®
CSV 2 / 5

Automated Thawing Systems

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Are you still using a manual water bath to thaw vials?

Frustrated by inconsistent thaw profiles and cell viability?

Check out the NEW! ThawSTAR® CSV 2 and ThawSTAR® CSV 5 Automated Thawing Systems, now available for CellSeal® Cryogenic Vials and CellSeal® Connect Vials.

ThawSTAR® CSV 2 / 5 Automated Thawing Systems

  • <3 min thaw time
  • Water-free
  • Qualifiable
  • Programmed precision
  • Safer samples
Sexton Biotechnologies

How can we help you?

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Get in touch

BioLife Solutions Inc.
3303 Monte Villa Parkway,
Suite 310, Bothell , WA 98021 USA

For assistance, please call us Monday
through Friday (9:00 am to 5:00 pm PST) at:

Toll Free (North America): +1.866.424.6543
Direct: +1.425.402.1400
Fax: +1.425.402.1433

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