HypoThermosol biopreservation media is a novel, engineered, optimized hypothermic storage and shipping media product.
Serum-free, protein-free HypoThermosol is designed to provide maximum storage and shipping stability for biologics at 2-8°C.
This proprietary, optimized formulation mitigates temperature-induced molecular cell stress responses that occur during chilling and re-warming of biologics, intermediate products, and final cell products intended for research and clinical applications.
Similar to our companion freeze media CryoStor, HypoThermosol FRS includes components that scavenge free radicals, provide pH buffering, oncotic/osmotic support, energy substrates, and ionic concentrations that balance the intracellular state at low temperatures.
Across a broad spectrum of cell and tissue types, HypoThermosol product has proven much more effective in reducing post-preservation necrosis and apoptosis as compared to commercial and home-brew isotonic and extracellular formulations. This results in greatly extended shelf life and improved post-preservation viability.
HypoThermosol meets USP <71> Sterility and USP <85> Endotoxin testing standards, and is manufactured under cGMP.
HypoThermosol is packaged in four convenient alternatives:
HypoThermosol FRS 10mL Vial
Sterile vial filled with 10mL of HypoThermosol, closed with a flip top septum for needle access. Designed for initial product sampling or single-use applications.
HypoThermosol FRS 100mL Bottle
Nalgene PETG square media bottle with a screw cap, designed for applications requiring a larger volume of HypoThermosol, where repeated access to the container is not expected.
HypoThermosol FRS 500mL Bottle
Nalgene PETG square media bottle. Designed for even larger volume applications such as tissue transport and storage.
HypoThermosol FRS 500mL IV Bag
EVA media bag with syringe and spike ports. Designed for improved aseptic technique when aliquotting HypoThermosol for multiple doses or repeated processing.
Custom Orders
Please contact us for bulk or custom package configurations of HypoThermosol FRS.
HypoThermosol Performance Evidence
| Product | Part # | Package/Volume | List Price ($USD) | |
|---|---|---|---|---|
| HypoThermosol FRS 10mL Vial |
101373 | 1 x 10mL vial | $25 | ORDER |
| HypoThermosol FRS 100mL Bottle |
101102 | 1 x 100mL bottle | $170 | ORDER |
| HypoThermosol FRS 500mL Bottle |
101104 | 1 x 500mL bottle | $775 | ORDER |
| HypoThermosol FRS 500mL IV Bag |
101204 | 1 x 500mL IV bag | $785 | ORDER |






