HypoThermosol, the Preferred Medium for Hypothermic Storage

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Hypothermic Storage Abstracts.

Snyder, K.K., Baust, J.M., Van Buskirk, R.G., Baust, J.G. Improved Hypothermic Storage of Sensitive Primary Cell Systems. Cytotherapy, Vol. 7 Supp. 1, pg. 2, 2005.

Snyder, K.K., Baust, J.M., Van Buskirk, R.G., Baust, J.G. Assessment of Function and Metabolic Activity of Neonatal Cardiomyocytes Following Hypothermic Storage. Cryobiology, Vol. 47 No. 3, pg. 273, 2003. (P.L. Steponkus Crystal Award Recipient)

Mathew, A.J., Baust, J.G., and Van Buskirk, R.G. Enhanced hypothermic preservation of human renal cells. Cryobiology 43:357 (2001).

Mathew, A.J., Baust, J.G., and Van Buskirk, R.G. Enhanced hypothermic preservation of multiple human cell types. Cryobiology 43:383 (2001).

Mathew, A. J., Baust, J. M., Hollister, W.R., Al-Abdullah, I. H., Ricordi, C., Ban Buskirk, R. G., and Baust, J. G. Molecular biological analysis of cell death leads to improvement in the hypothermic solution, HypoThermosol. Cryobiology 41:335-6 (2000).

Mathew, A. J., Hollister, W. R., Baust, J. G., and Van Buskirk, R. G. Continued optimization of the cold storage solution HypoThermosol and implications of apoptosis. Cryobiology 37:398-9 (1998).

Wagerle, L.C., Taylor, M. J., Dahdah, N. S. and Russo, P. Effects of ultraprofound hypothermia on the ex vivo contractile response of cerebral arteries: Relevance to cerebrovascular dysfunction during cardiopulmonary bypass. Cryobiology 35:346 (1997).
Elrifai, A. M., Taylor, M. J., Shih, S-R., Bailes, J. E., Kiya, N., Wilberger, J. E., and Maroon, J. C. Hypothermic preservation of immature spinal cord using HypoThermosol for transplantation in the rat. Cryobiology 33:675 (1996).

Taylor, M. J., Snyder, M., Machen, L., Clark, R. E., and Baust, J. G. Functional survival of isolated rabbit hearts after cold storage in HypoThermosol modified with compounds that might promote retention and repletion of high energy phosphates. Cryobiology 33:620-1, (1996).

Taylor, M. J., Clark, R. E.; Snyder, M., Machen, L., and Baust, J. G. Static cold storage of isolated rabbit hearts in HypoThermosol: Influence of butanedione monoxime during short-term storage. Cryobiology 32:538-9 (1995).

Van Buskirk, R. G., Taylor, M. J., Rauch, J., Roberts, S., and Baust, J. G. Preservation of synthetic human skin in HypoThermosol. Cryobiology 32:591 (1995).

Van Buskirk, R. G., Taylor, M. J., Shen, R., Tang, W., Mathew, A., and Baust, J. G. Optimization of HypoThermosol using cultured cardiomyocytes and the fluorescent multiple endpoint assay. Cryobiology 32:590 (1995).

Taylor, M. J., Simon, D., Elrifai, A. M., Shih, S-R., Bailes, J. E., Baust, J. G., Maroon, J. C., and Diamond, D. L. A feasibility study in a canine model for using profound hypothermia and blood substitution with HypoThermosol to enable resuscitation after hemorrhagic shock. Cryobiology 31:592-3 (1994).

Taylor, M. J., Clark, R. E., and Baust, J. G. The importance of adenosine and glutathione as components of a new hypothermic blood substitute (HypoThermosol): Evaluation of myocardial protection at 7°C using an isolated working rabbit heart model. Cryobiology 30:593-4 (1994).